Steerable laser probe

ABSTRACT

A steerable laser probe may include a handle having a handle, a housing sleeve, a first portion of the housing sleeve having a first stiffness, a second portion of the housing sleeve having a second stiffness, an actuation control of the handle, an optic fiber disposed in an inner bore of the handle and the housing sleeve, and a shape memory wire having a pre-formed curve. An actuation of the actuation control may be configured to gradually curve the housing sleeve and the optic fiber. An actuation of the actuation control may be configured to gradually straighten the housing sleeve and the optic fiber.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application is a continuation of prior application Ser. No.14/943,424 filed Nov. 17, 2015.

FIELD OF THE INVENTION

The present disclosure relates to a surgical instrument, and, moreparticularly, to a steerable laser probe.

BACKGROUND OF THE INVENTION

A wide variety of ophthalmic procedures require a laser energy source.For example, ophthalmic surgeons may use laser photocoagulation to treatproliferative retinopathy. Proliferative retinopathy is a conditioncharacterized by the development of abnormal blood vessels in the retinathat grow into the vitreous humor. Ophthalmic surgeons may treat thiscondition by energizing a laser to cauterize portions of the retina toprevent the abnormal blood vessels from growing and hemorrhaging.

In order to increase the chances of a successful laser photocoagulationprocedure, it is important that a surgeon is able aim the laser at aplurality of targets within the eye, e.g., by guiding or moving thelaser from a first target to a second target within the eye. It is alsoimportant that the surgeon is able to easily control a movement of thelaser. For example, the surgeon must be able to easily direct a laserbeam by steering the beam to a first position aimed at a first target,guide the laser beam from the first position to a second position aimedat a second target, and hold the laser beam in the second position.Accordingly, there is a need for a surgical laser probe that can beeasily guided to a plurality of targets within the eye.

BRIEF SUMMARY OF THE INVENTION

The present disclosure presents a steerable laser probe. Illustratively,a steerable laser probe may comprise a handle having a handle distal endand a handle proximal end, a housing sleeve having a housing sleevedistal end and a housing sleeve proximal end, a first portion of thehousing sleeve having a first stiffness, a second portion of the housingsleeve having a second stiffness, an actuation control of the handle, anoptic fiber disposed in an inner bore of the handle and the housingsleeve, and a shape memory wire having a pre-formed curve. In one ormore embodiments, an actuation of the actuation control may beconfigured to gradually curve the housing sleeve and the optic fiber.Illustratively, an actuation of the actuation control may be configuredto gradually straighten the housing sleeve and the optic fiber.

BRIEF DESCRIPTION OF THE DRAWINGS

The above and further advantages of the present invention may be betterunderstood by referring to the following description in conjunction withthe accompanying drawings in which like reference numerals indicateidentical or functionally similar elements:

FIGS. 1A and 1B are schematic diagrams illustrating a handle;

FIG. 2 is a schematic diagram illustrating an exploded view of asteerable laser probe assembly;

FIGS. 3A, 3B, 3C, 3D, and 3E are schematic diagrams illustrating agradual curving of an optic fiber;

FIGS. 4A, 4B, 4C, 4D, and 4E are schematic diagrams illustrating agradual straightening of an optic fiber.

DETAILED DESCRIPTION OF AN ILLUSTRATIVE EMBODIMENT

FIGS. 1A and 1B are schematic diagrams illustrating a handle 100. FIG.1A illustrates a top view of handle 100. Illustratively, handle 100 maycomprise a handle distal end 101 and a handle proximal end 102. In oneor more embodiments, handle 100 may comprise a handle end cap 105 havinga handle end cap distal end 106 and a handle end cap proximal end 107,an actuation mechanism 110 having an actuation mechanism distal end 111and an actuation mechanism proximal end 112, a fixation mechanismhousing 115, an actuation control 120, a handle base 130 having a handlebase distal end 131 and a handle base proximal end 132, and an actuationcontrol guide 140 having an actuation control guide distal end 141 andan actuation control guide proximal end 142. Illustratively, handle 100may be manufactured from any suitable material, e.g., polymers, metals,metal alloys, etc., or from any combination of suitable materials.

FIG. 1B illustrates a cross-sectional view of handle 100.Illustratively, handle 100 may comprise an optic fiber guide 150, anactuation mechanism guide 160, an inner bore 170, a shape memory wirehousing 175, a pressure mechanism housing 180, and a housing sleevehousing 190. Handle end cap 105, actuation mechanism 110, actuationcontrol 120, and handle base 130 may be manufactured from any suitablematerial, e.g., polymers, metals, metal alloys, etc., or from anycombination of suitable materials.

Illustratively, actuation mechanism 110 may be disposed within handleend cap 105 and handle base 130. In one or more embodiments, actuationmechanism 110 may be configured to actuate within handle end cap 105 andhandle base 130, e.g., actuation mechanism 110 may be configured toactuate within actuation mechanism guide 160. Illustratively, a portionof actuation mechanism guide 160 may be configured to facilitate anactuation of actuation mechanism 110 within actuation mechanism guide160. In one or more embodiments, a portion of actuation mechanism guide160 may comprise a lubricant, e.g., Teflon, configured to facilitate anactuation of actuation mechanism 110 within actuation mechanism guide160. Illustratively, actuation control 120 may be disposed withinactuation control guide 140, e.g., actuation control 120 may beconfigured to actuate within actuation control guide 140. In one or moreembodiments, an actuation of actuation control 120 within actuationcontrol guide 140 may be configured to actuate actuation mechanism 110within actuation mechanism guide 160.

Illustratively, an actuation of actuation control 120 within actuationcontrol guide 140, e.g., towards actuation control guide distal end 141and away from actuation control guide proximal end 142, may beconfigured to actuate actuation mechanism 110 within actuation mechanismguide 160, e.g., towards handle distal end 101 and away from handleproximal end 102. In one or more embodiments, an actuation of actuationmechanism 110 towards handle distal end 101 and away from handleproximal end 102 may be configured to extend shape memory wire housing175 relative to housing sleeve housing 190. Illustratively, an actuationof actuation control 120 within actuation control guide 140, e.g.,towards actuation control guide proximal end 142 and away from actuationcontrol guide distal end 141, may be configured to actuate actuationmechanism 110 within actuation mechanism guide 160, e.g., towards handleproximal end 102 and away from handle distal end 101. In one or moreembodiments, an actuation of actuation mechanism 110 towards handleproximal end 102 and away from handle distal end 101 may be configuredto retract shape memory wire housing 175 relative to housing sleevehousing 190.

FIG. 2 is a schematic diagram illustrating an exploded view of asteerable laser probe assembly 200. Illustratively, a steerable laserprobe assembly 200 may comprise a handle end cap 105 having a handle endcap distal end 106 and a handle end cap proxies mal end 107; anactuation mechanism 110 having an actuation mechanism distal end 111 andan actuation mechanism proximal end 112; an actuation control 120; ahandle base 130 having a handle base distal end 131 and a handle baseproximal end 132; a shape memory wire 210 having a shape memory wiredistal end 211, a shape memory wire proximal end 212, and a pre-formedcurve 215; a housing sleeve 220 having a housing sleeve distal end 221,a housing sleeve proximal end 222, a first housing sleeve portion 225,and a second housing sleeve portion 226; an optic fiber 230 having anoptic fiber distal end 231 and an optic fiber proximal end 232; a lightsource interface 240; and a fixation mechanism 250. In one or moreembodiments, light source interface 240 may be configured to interfacewith optic fiber 230, e.g., at optic fiber proximal end 232.Illustratively, light source interface 240 may comprise a standard lightsource connecter, e.g., an SMA connector.

In one or more embodiments, housing sleeve 220 may be manufactured withdimensions configured for microsurgical procedures. Housing sleeve 220may be manufactured from any suitable material, e.g., polymers, metals,metal alloys, etc., or from any combination of suitable materials. Inone or more embodiments, first housing sleeve portion 225 may have afirst stiffness. Illustratively, second housing sleeve portion 226 mayhave a second stiffness. In one or more embodiments, the secondstiffness may be greater than the first stiffness. Illustratively, firsthousing sleeve portion 225 may comprise a first material having a firststiffness. In one or more embodiments, second housing sleeve portion 226may comprise a second material having a second stiffness.Illustratively, the second stiffness may be greater than the firststiffness.

In one or more embodiments, housing sleeve 220 may comprise anon-uniform inner diameter or a non-uniform outer diameter, e.g., tovary a stiffness of one or more portions of housing sleeve 220.Illustratively, a first housing sleeve portion 225 may comprise a firstinner diameter of housing sleeve 220 and a second housing sleeve portion226 may comprise a second inner diameter of housing sleeve 220. In oneor more embodiments, the first inner diameter of housing sleeve 220 maybe larger than the second inner diameter of housing sleeve 220.Illustratively, a first housing sleeve portion 225 may comprise a firstouter diameter of housing sleeve 220 and a second housing sleeve portion226 may comprise a second outer diameter of housing sleeve 220. In oneor more embodiments, the first outer diameter of housing sleeve 220 maybe smaller than the second outer diameter of housing sleeve 220.

In one or more embodiments, first housing sleeve portion 225 maycomprise one or more apertures configured to produce a first stiffnessof first housing sleeve portion 225. Illustratively, second housingsleeve portion 226 may comprise a solid portion of housing sleeve 220having a second stiffness. In one or more embodiments, the secondstiffness may be greater than the first stiffness. Illustratively, firsthousing sleeve portion 225 may comprise one or more apertures configuredto produce a first stiffness of first housing sleeve portion 225. In oneor more embodiments, second housing sleeve portion 226 may comprise oneor more apertures configured to produce a second stiffness of secondhousing sleeve portion 226. Illustratively, the second stiffness may begreater than the first stiffness.

In one or more embodiments, first housing sleeve portion 225 maycomprise a plurality of slits configured to separate one or more solidportions of housing sleeve 220. Illustratively, a plurality of slits maybe cut, e.g., laser cut, into first housing sleeve portion 225. In oneor more embodiments, first housing sleeve portion 225 may comprise aplurality of slits configured to minimize a force of friction betweenhousing sleeve 220 and a cannula, e.g., as housing sleeve 220 isinserted into the cannula or as housing sleeve 220 is extracted from thecannula. For example, each slit of the plurality of slits may compriseone or more arches configured to minimize a force of friction betweenhousing sleeve 220 and a cannula.

Illustratively, a portion of housing sleeve 220 may be fixed to aportion of handle base 130, e.g., housing sleeve proximal end 222 may befixed to handle base distal end 131. In one or more embodiments, aportion of housing sleeve 220 may be fixed to a portion of handle base130, e.g., by an adhesive or any suitable fixation means.Illustratively, a portion of housing sleeve 220 may be fixed to aportion of handle 100, e.g., housing sleeve proximal end 222 may befixed to handle distal end 101. In one or more embodiments, a portion ofhousing sleeve 220 may be fixed to a portion of handle 100, e.g., by anadhesive or any suitable fixation means. Illustratively, a portion ofhousing sleeve 220 may be disposed within housing sleeve housing 190,e.g., housing sleeve proximal end 222 may be disposed within housingsleeve housing 190. In one or more embodiments, a portion of housingsleeve 220 may be fixed within housing sleeve housing 190, e.g., by anadhesive or any suitable fixation means. For example, a portion ofhousing sleeve 220 may be fixed within housing sleeve housing 190 by apress fit, a setscrew, etc.

Illustratively, optic fiber 230 may be configured to transmit light,e.g., optic fiber 230 may be configured to transmit laser light,illumination light, etc. In one or more embodiments, optic fiber 230 maybe disposed in optic fiber guide 150, actuation mechanism guide 160,inner bore 170, housing sleeve housing 190, and housing sleeve 220.Illustratively, optic fiber 230 may be disposed within housing sleeve220 wherein optic fiber distal end 231 may be adjacent to housing sleevedistal end 221. In one or more embodiments, optic fiber 230 may bedisposed within housing sleeve 220 wherein a portion of optic fiber 230may be adjacent to a portion of second housing sleeve portion 226.Illustratively, a portion of optic fiber 230 may be fixed to a portionof housing sleeve 220, e.g., by an adhesive or any suitable fixationmeans.

In one or more embodiments, at least a portion of shape memory wire 210may comprise a shape memory material, e.g., Nitinol. Illustratively,shape memory wire 210 may comprise a pre-formed curve 215. In one ormore embodiments, pre-formed curve 215 may comprise a shape memorymaterial, e.g., Nitinol. In one or more embodiments, shape memory wire210 may be disposed in shape memory wire housing 175, actuationmechanism guide 160, housing sleeve housing 190, and housing sleeve 220.Illustratively, shape memory wire distal end 211 may be disposed withinhousing sleeve 220. In one or more embodiments, at least a portion ofpre-formed curve 215 may be disposed within housing sleeve 220.Illustratively, shape memory wire proximal end 212 may be disposedwithin shape memory wire housing 175. In one or more embodiments, aportion of shape memory wire 210 may be fixed within shape memory wirehousing 175, e.g., by an adhesive or any suitable fixation means.Illustratively, fixation mechanism 250 may be configured to fix aportion of shape memory wire 210 to actuation mechanism 110. In one ormore embodiments, fixation mechanism 250 may be disposed within fixationmechanism housing 115. Illustratively, a portion of fixation mechanism250 may be disposed in shape memory wire housing 175. In one or moreembodiments, fixation mechanism 250 may comprise a setscrew configuredto fix shape memory wire 210 in a position relative to actuationmechanism 110. Illustratively, shape memory wire 210 may be fixed withinshape memory wire housing 175, e.g., by a press fit or any suitablefixation means.

In one or more embodiments, an actuation of actuation control 120 withinactuation control guide 140, e.g., towards actuation control guidedistal end 141 and away from actuation control guide proximal end 142,may be configured to actuate actuation mechanism 110 within actuationmechanism guide 160, e.g., towards handle distal end 101 and away fromhandle proximal end 102. Illustratively, an actuation of actuationmechanism 110 towards handle distal end 101 and away from handleproximal end 102 may be configured to extend shape memory wire housing175 relative to housing sleeve housing 190. In one or more embodiments,an extension of shape memory wire housing 175 relative to housing sleevehousing 190 may be configured to extend shape memory wire 210 relativeto housing sleeve 220. Illustratively, an extension of shape memory wire210 relative to housing sleeve 220 may be configured to extendpre-formed curve 215 within housing sleeve 220, e.g., towards housingsleeve distal end 221 and away from housing sleeve proximal end 222. Inone or more embodiments, an extension of pre-formed curve 215 towardshousing sleeve distal end 221 and away from housing sleeve proximal end222 may be configured to extend a portion of pre-formed curve 215 over aportion of first housing sleeve portion 225. Illustratively, a portionof housing sleeve 220 may be configured to generally straightenpre-formed curve 215. In one or more embodiments, an extension ofpre-formed curve 215 over a portion of first housing sleeve portion 225may be configured to cause a generally straightened pre-formed curve 215to gradually curve. Illustratively, a stiffness of first housing sleeveportion 225 may be configured to allow pre-formed curve 215 to graduallycurve. In one or more embodiments, a gradual curving of shape memorywire 210 within housing sleeve 220 may be configured to gradually curvehousing sleeve 220. Illustratively, a gradual curving of housing sleeve220 may be configured to gradually curve optic fiber 230. In one or moreembodiments, an actuation of actuation control 120 within actuationcontrol guide 140, e.g., towards actuation control guide distal end 141and away from actuation control guide proximal end 142, may beconfigured to gradually curve optic fiber 230. Illustratively, anextension of actuation control 120 relative to actuation control guideproximal end 142 may be configured to gradually curve optic fiber 230.

In one or more embodiments, an actuation of actuation control 120 withinactuation control guide 140, e.g., towards actuation control guideproximal end 142 and away from actuation control guide distal end 141,may be configured to actuate actuation mechanism 110 within actuationmechanism guide 160, e.g., towards handle proximal end 102 and away fromhandle distal end 101. Illustratively, an actuation of actuationmechanism 110 towards handle proximal end 102 and away from handledistal end 101 may be configured to retract shape memory wire housing175 relative to housing sleeve housing 190. In one or more embodiments,a retraction of shape memory wire housing 175 relative to housing sleevehousing 190 may be configured to retract shape memory wire 210 relativeto housing sleeve 220. Illustratively, a retraction of shape memory wire210 relative to housing sleeve 220 may be configured to retractpre-formed curve 215 within housing sleeve 220, e.g., towards housingsleeve proximal end 222 and away from housing sleeve distal end 221. Inone or more embodiments, a retraction of pre-formed curve 215 towardshousing sleeve proximal end 222 and away from housing sleeve distal end221 may be configured to retract a portion of pre-formed curve 215 awayfrom a portion of first housing sleeve portion 225. Illustratively, aportion of housing sleeve 220 may be configured to generally straightenpre-formed curve 215. In one or more embodiments, a retraction ofpre-formed curve 215 away from a portion of first housing sleeve portion225 may be configured to cause pre-formed curve 215 to graduallystraighten. Illustratively, a stiffness of housing sleeve 220 may beconfigured to gradually straighten pre-formed curve 215. In one or moreembodiments, a gradual straightening of shape memory wire 210 withinhousing sleeve 220 may be configured to gradually straighten housingsleeve 220. Illustratively, a gradual straightening of housing sleeve220 may be configured to gradually straighten optic fiber 230. In one ormore embodiments, an actuation of actuation control 120 within actuationcontrol guide 140, e.g., towards actuation control guide proximal end142 and away from actuation control guide distal end 141, may beconfigured to gradually straighten optic fiber 230. Illustratively, aretraction of actuation control 120 relative to actuation control guideproximal end 142 may be configured to gradually straighten optic fiber230.

FIGS. 3A, 3B, 3C, 3D, and 3E are schematic diagrams illustrating agradual curving of an optic fiber 230. FIG. 3A illustrates a straightoptic fiber 300. In one or more embodiments, optic fiber 230 maycomprise a straight optic fiber 300, e.g., when actuation control 120 isfully retracted relative to actuation control guide proximal end 142.Illustratively, optic fiber 230 may comprise a straight optic fiber 300,e.g., when actuation mechanism 110 is fully retracted relative to handleproximal end 102. In one or more embodiments, optic fiber 230 maycomprise a straight optic fiber 300, e.g., when shape memory wire 210 isfully retracted relative to housing sleeve 220. Illustratively, opticfiber 230 may comprise a straight optic fiber 300, e.g., when pre-formedcurve 215 is fully retracted relative to first housing sleeve portion225. In one or more embodiments, optic fiber 230 may comprise a straightoptic fiber 300, e.g., when pre-formed curve 215 is generallystraightened by a portion of housing sleeve 220. Illustratively, a linetangent to optic fiber distal end 231 may be parallel to a line tangentto housing sleeve proximal end 222, e.g., when optic fiber 230 comprisesa straight optic fiber 300.

FIG. 3B illustrates an optic fiber in a first curved position 310. Inone or more embodiments, an actuation of actuation control 120 withinactuation control guide 140, e.g., towards actuation control guidedistal end 141 and away from actuation control guide proximal end 142,may be configured to gradually curve optic fiber 230 from a straightoptic fiber 300 to an optic fiber in a first curved position 310.Illustratively, an actuation of actuation control 120 towards actuationcontrol guide distal end 141 and away from actuation control guideproximal end 142 may be configured to extend actuation mechanism 110within actuation mechanism guide 160, e.g., towards handle distal end101 and away from handle proximal end 102. In one or more embodiments,an extension of actuation mechanism 110 within actuation mechanism guide160 may be configured to extend shape memory wire 210 relative tohousing sleeve 220. Illustratively, an extension of shape memory wire210 relative to housing sleeve 220 may be configured to extendpre-formed curve 215 within housing sleeve 220, e.g., towards housingsleeve distal end 221 and away from housing sleeve proximal end 222. Inone or more embodiments, an extension of pre-formed curve 215 withinhousing sleeve 220 may be configured to extend a portion of pre-formedcurve 215 over first housing sleeve portion 225. Illustratively, anextension of a portion of pre-formed curve 215 over first housing sleeveportion 225 may be configured to gradually curve housing sleeve 220. Inone or more embodiments, a gradual curving of housing sleeve 220 may beconfigured to gradually curve optic fiber 230, e.g., from a straightoptic fiber 300 to an optic fiber in a first curved position 310.Illustratively, a line tangent to optic fiber distal end 231 mayintersect a line tangent to housing sleeve proximal end 222 at a firstangle, e.g., when optic fiber 230 comprises an optic fiber in a firstcurved position 310. In one or more embodiments, the first angle maycomprise any angle greater than zero degrees. For example, the firstangle may comprise a 45 degree angle.

FIG. 3C illustrates an optic fiber in a second curved position 320. Inone or more embodiments, an actuation of actuation control 120 withinactuation control guide 140, e.g., towards actuation control guidedistal end 141 and away from actuation control guide proximal end 142,may be configured to gradually curve optic fiber 230 from an optic fiberin a first curved position 310 to an optic fiber in a second curvedposition 320. Illustratively, an actuation of actuation control 120towards actuation control guide distal end 141 and away from actuationcontrol guide proximal end 142 may be configured to extend actuationmechanism 110 within actuation mechanism guide 160, e.g., towards handledistal end 101 and away from handle proximal end 102. In one or moreembodiments, an extension of actuation mechanism 110 within actuationmechanism guide 160 may be configured to extend shape memory wire 210relative to housing sleeve 220. Illustratively, an extension of shapememory wire 210 relative to housing sleeve 220 may be configured toextend pre-formed curve 215 within housing sleeve 220, e.g., towardshousing sleeve distal end 221 and away from housing sleeve proximal end222. In one or more embodiments, an extension of pre-formed curve 215within housing sleeve 220 may be configured to extend a portion ofpre-formed curve 215 over first housing sleeve portion 225.Illustratively, an extension of a portion of pre-formed curve 215 overfirst housing sleeve portion 225 may be configured to gradually curvehousing sleeve 220. In one or more embodiments, a gradual curving ofhousing sleeve 220 may be configured to gradually curve optic fiber 230,e.g., from an optic fiber in a first curved position 310 to an opticfiber in a second curved position 320. Illustratively, a line tangent tooptic fiber distal end 231 may intersect a line tangent to housingsleeve proximal end 222 at a second angle, e.g., when optic fiber 230comprises an optic fiber in a second curved position 320. In one or moreembodiments, the second angle may comprise any angle greater than thefirst angle. For example, the second angle may comprise a 90 degreeangle.

FIG. 3D illustrates an optic fiber in a third curved position 330. Inone or more embodiments, an actuation of actuation control 120 withinactuation control guide 140, e.g., towards actuation control guidedistal end 141 and away from actuation control guide proximal end 142,may be configured to gradually curve optic fiber 230 from an optic fiberin a second curved position 320 to an optic fiber in a third curvedposition 330. Illustratively, an actuation of actuation control 120towards actuation control guide distal end 141 and away from actuationcontrol guide proximal end 142 may be configured to extend actuationmechanism 110 within actuation mechanism guide 160, e.g., towards handledistal end 101 and away from handle proximal end 102. In one or moreembodiments, an extension of actuation mechanism 110 within actuationmechanism guide 160 may be configured to extend shape memory wire 210relative to housing sleeve 220. Illustratively, an extension of shapememory wire 210 relative to housing sleeve 220 may be configured toextend pre-formed curve 215 within housing sleeve 220, e.g., towardshousing sleeve distal end 221 and away from housing sleeve proximal end222. In one or more embodiments, an extension of pre-formed curve 215within housing sleeve 220 may be configured to extend a portion ofpre-formed curve 215 over first housing sleeve portion 225.Illustratively, an extension of a portion of pre-formed curve 215 overfirst housing sleeve portion 225 may be configured to gradually curvehousing sleeve 220. In one or more embodiments, a gradual curving ofhousing sleeve 220 may be configured to gradually curve optic fiber 230,e.g., from an optic fiber in a second curved position 320 to an opticfiber in a third curved position 330. Illustratively, a line tangent tooptic fiber distal end 231 may intersect a line tangent to housingsleeve proximal end 222 at a third angle, e.g., when optic fiber 230comprises an optic fiber in a third curved position 330. In one or moreembodiments, the third angle may comprise any angle greater than thesecond angle. For example, the third angle may comprise a 135 degreeangle.

FIG. 3E illustrates an optic fiber in a fourth curved position 340. Inone or more embodiments, an actuation of actuation control 120 withinactuation control guide 140, e.g., towards actuation control guidedistal end 141 and away from actuation control guide proximal end 142,may be configured to gradually curve optic fiber 230 from an optic fiberin a second curved position 320 to an optic fiber in a third curvedposition 330. Illustratively, an actuation of actuation control 120towards actuation control guide distal end 141 and away from actuationcontrol guide proximal end 142 may be configured to extend actuationmechanism 110 within actuation mechanism guide 160, e.g., towards handledistal end 101 and away from handle proximal end 102. In one or moreembodiments, an extension of actuation mechanism 110 within actuationmechanism guide 160 may be configured to extend shape memory wire 210relative to housing sleeve 220. Illustratively, an extension of shapememory wire 210 relative to housing sleeve 220 may be configured toextend pre-formed curve 215 within housing sleeve 220, e.g., towardshousing sleeve distal end 221 and away from housing sleeve proximal end222. In one or more embodiments, an extension of pre-formed curve 215within housing sleeve 220 may be configured to extend a portion ofpre-formed curve 215 over first housing sleeve portion 225.Illustratively, an extension of a portion of pre-formed curve 215 overfirst housing sleeve portion 225 may be configured to gradually curvehousing sleeve 220. In one or more embodiments, a gradual curving ofhousing sleeve 220 may be configured to gradually curve optic fiber 230,e.g., from an optic fiber in a third curved position 330 to an opticfiber in a fourth curved position 340. Illustratively, a line tangent tooptic fiber distal end 231 may be parallel to a line tangent to housingsleeve proximal end 222, e.g., when optic fiber 230 comprises an opticfiber in a fourth curved position 340.

In one or more embodiments, one or more properties of a steerable laserprobe may be adjusted to attain one or more desired steerable laserprobe features. Illustratively, a length that housing sleeve distal end221 extends from handle distal end 101 may be adjusted to vary an amountof actuation of actuation control 120 configured to curve housing sleeve220 to a particular curved position. In one or more embodiments, astiffness of first housing sleeve portion 225 or a stiffness of secondhousing sleeve portion 226 may be adjusted to vary an amount ofactuation of actuation control 120 configured to curve housing sleeve220 to a particular curved position. Illustratively, a materialcomprising first housing sleeve portion 225 or a material comprisingsecond housing sleeve portion 226 may be adjusted to vary an amount ofactuation of actuation control 120 configured to curve housing sleeve220 to a particular curved position.

In one or more embodiments, a number of apertures in housing sleeve 220may be adjusted to vary an amount of actuation of actuation control 120configured to curve housing sleeve 220 to a particular curved position.Illustratively, a location of one or more apertures in housing sleeve220 may be adjusted to vary an amount of actuation of actuation control120 configured to curve housing sleeve 220 to a particular curvedposition. In one or more embodiments, a geometry of one or moreapertures in housing sleeve 220 may be adjusted to vary an amount ofactuation of actuation control 120 configured to curve housing sleeve220 to a particular curved position. Illustratively, a geometry of oneor more apertures in housing sleeve 220 may be uniform, e.g., eachaperture of the one or more apertures may have a same geometry. In oneor more embodiments, a geometry of one or more apertures in housingsleeve 220 may be non-uniform, e.g., a first aperture in housing sleeve220 may have a first geometry and a second aperture in housing sleeve220 may have a second geometry.

Illustratively, a stiffness of first housing sleeve portion 225 or astiffness of second housing sleeve portion 226 may be adjusted to vary abend radius of housing sleeve 220. In one or more embodiments, astiffness of first housing sleeve portion 225 or a stiffness of secondhousing sleeve portion 226 may be adjusted to vary a radius of curvatureof housing sleeve 220, e.g., when housing sleeve 220 is in a particularcurved position. Illustratively, a number of apertures in housing sleeve220 may be adjusted to vary a bend radius of housing sleeve 220. In oneor more embodiments, a number of apertures in housing sleeve 220 may beadjusted to vary a radius of curvature of housing sleeve 220, e.g., whenhousing sleeve 220 is in a particular curved position. Illustratively, alocation or a geometry of one or more apertures in housing sleeve 220may be adjusted to vary a bend radius of housing sleeve 220. In one ormore embodiments, a location or a geometry of one or more apertures inhousing sleeve 220 may be adjusted to vary a radius of curvature ofhousing sleeve 220, e.g., when housing sleeve 220 is in a particularcurved position.

In one or more embodiments, a geometry of actuation mechanism 110 may beadjusted to vary an amount of actuation of actuation control 120configured to curve housing sleeve 220 to a particular curved position.Illustratively, a geometry of actuation mechanism guide 160 may beadjusted to vary an amount of actuation of actuation control 120configured to curve housing sleeve 220 to a particular curved position.In one or more embodiments, a geometry of handle end cap 105 or ageometry of handle base 130 may be adjusted to vary an amount ofactuation of actuation control 120 configured to curve housing sleeve220 to a particular curved position. Illustratively, a length of shapememory wire 210 may be adjusted to vary an amount of actuation ofactuation control 120 configured to curve housing sleeve 220 to aparticular curved position. In one or more embodiments, a geometry ofpre-formed curve 215 may be adjusted to vary an amount of actuation ofactuation control 120 configured to curve housing sleeve 220 to aparticular curved position. Illustratively, a location of pre-formedcurve 215 relative to shape memory wire distal end 211 may be adjustedto vary an amount of actuation of actuation control 120 configured tocurve housing sleeve 220 to a particular curved position.

In one or more embodiments, at least a portion of optic fiber 230 may beenclosed in an optic fiber sleeve configured to, e.g., protect opticfiber 230, vary a stiffness of optic fiber 230, vary an optical propertyof optic fiber 230, etc. Illustratively, optic fiber 230 may comprise abuffer, a cladding disposed in the buffer, and a core disposed in thecladding. In one or more embodiments, at least a portion of optic fiber230 may comprise a buffer configured to protect an optical property ofoptic fiber 230. Illustratively, at least a portion of optic fiber 230may comprise a buffer configured to protect an optical layer of opticfiber 230, e.g., the buffer may protect an optical layer of a curvedportion of optic fiber 230. In one or more embodiments, at least aportion of optic fiber 230 may comprise a polyimide buffer configured toprotect an optical property of optic fiber 230. For example, at least aportion of optic fiber 230 may comprise a Kapton buffer configured toprotect an optical property of optic fiber 230.

In one or more embodiments, a steerable laser probe may comprise apressure mechanism configured to provide a force. Illustratively, apressure mechanism may be disposed within pressure mechanism housing180. In one or more embodiments, a pressure mechanism may be configuredto provide a constant force. Illustratively, a pressure mechanism may beconfigured to provide a variable force. In one or more embodiments, apressure mechanism may be configured to provide a resistive force, e.g.,to resist an extension of actuation mechanism 110 relative to handleproximal end 102. Illustratively, a pressure mechanism may be configuredto provide a facilitating force, e.g., to facilitate a retraction ofactuation mechanism 110 relative to handle proximal end 102. In one ormore embodiments, a pressure mechanism may comprise a spring or a coil.Illustratively, a pressure mechanism may comprise a pneumatic system orany system configured to provide a force.

Illustratively, handle 100 may comprise one or more detents configuredto temporarily house an actuation control 120. In one or moreembodiments, actuation control guide 140 may comprise one or moredetents configured to temporarily fix actuation control 120 in aposition relative to handle proximal end 102. Illustratively, a surgeonmay actuate actuation control 120 into a detent of an actuation controlguide 140, e.g., to temporarily fix actuation control 120 in a positionrelative to handle proximal end 102. In one or more embodiments,temporarily fixing actuation control 120 in a position relative tohandle proximal end 102 may be configured to temporarily fix housingsleeve 220 in a particular curved position. Illustratively, a surgeonmay actuate an actuation control 120 out from a detent of an actuationcontrol guide 140, e.g., to adjust an amount of actuation of actuationcontrol 120 relative to handle proximal end 102. In one or moreembodiments, adjusting an amount of actuation of actuation control 120relative to handle proximal end 102 may be configured to adjust acurvature of housing sleeve 220.

FIGS. 4A, 4B, 4C, 4D, and 4E are schematic diagrams illustrating agradual straightening of an optic fiber 230. FIG. 4A illustrates a fullycurved optic fiber 400. In one or more embodiments, optic fiber 230 maycomprise a fully curved optic fiber 400, e.g., when actuation control120 is fully extended relative to actuation control guide proximal end142. Illustratively, optic fiber 230 may comprise a fully curved opticfiber 400, e.g., when actuation mechanism 110 is fully extended relativeto handle proximal end 102. In one or more embodiments, optic fiber 230may comprise a fully curved optic fiber 400, e.g., when shape memorywire 210 is fully extended relative to housing sleeve 220.Illustratively, optic fiber 230 may comprise a fully curved optic fiber400, e.g., when pre-formed curve 215 is fully extended over firsthousing sleeve portion 225. In one or more embodiments, a line tangentto optic fiber distal end 231 may be parallel to a line tangent tohousing sleeve proximal end 222, e.g., when optic fiber 230 comprises afully curved optic fiber 400.

FIG. 4B illustrates an optic fiber in a first partially straightenedposition 410. In one or more embodiments, an actuation of actuationcontrol 120 within actuation control guide 140, e.g., towards actuationcontrol guide proximal end 142 and away from actuation control guidedistal end 141, may be configured to gradually straighten optic fiber230 from a fully curved optic fiber 400 to an optic fiber in a firstpartially straightened position 410. Illustratively, an actuation ofactuation control 120 towards actuation control guide proximal end 142and away from actuation control guide distal end 141 may be configuredto retract actuation mechanism 110 within actuation mechanism guide 160,e.g., towards handle proximal end 102 and away from handle distal end101. In one or more embodiments, a retraction of actuation mechanism 110within actuation mechanism guide 160 may be configured to retract shapememory wire 210 relative to housing sleeve 220. Illustratively, aretraction of shape memory wire 210 relative to housing sleeve 220 maybe configured to retract pre-formed curve 215 within housing sleeve 220,e.g., towards housing sleeve proximal end 222 and away from housingsleeve distal end 221. In one or more embodiments, a retraction ofpre-formed curve 215 within housing sleeve 220 may be configured toretract a portion of pre-formed curve 215 away from first housing sleeveportion 225, e.g., into a portion of housing sleeve 220 configured togenerally straighten pre-formed curve 215. Illustratively, a retractionof a portion of pre-formed curve 215 away from first housing sleeveportion 225, e.g., into a portion of housing sleeve 220 configured togenerally straighten pre-formed curve 215, may be configured togradually straighten housing sleeve 220. In one or more embodiments, agradual straightening of housing sleeve 220 may be configured togradually straighten optic fiber 230, e.g., from a fully curved opticfiber 400 to an optic fiber in a first partially straightened position410. In one or more embodiments, a line tangent to optic fiber distalend 231 may intersect a line tangent to housing sleeve proximal end 222at a first partially straightened angle, e.g., when optic fiber 230comprises an optic fiber in a first partially straightened position 410.Illustratively, the first partially straightened angle may comprise anyangle less than 180 degrees. For example, the first partiallystraightened angle may comprise a 135 degree angle.

FIG. 4C illustrates an optic fiber in a second partially straightenedposition 420. In one or more embodiments, an actuation of actuationcontrol 120 within actuation control guide 140, e.g., towards actuationcontrol guide proximal end 142 and away from actuation control guidedistal end 141, may be configured to gradually straighten optic fiber230 from an optic fiber in a first partially straightened position 410to an optic fiber in a second partially straightened position 420.Illustratively, an actuation of actuation control 120 towards actuationcontrol guide proximal end 142 and away from actuation control guidedistal end 141 may be configured to retract actuation mechanism 110within actuation mechanism guide 160, e.g., towards handle proximal end102 and away from handle distal end 101. In one or more embodiments, aretraction of actuation mechanism 110 within actuation mechanism guide160 may be configured to retract shape memory wire 210 relative tohousing sleeve 220. Illustratively, a retraction of shape memory wire210 relative to housing sleeve 220 may be configured to retractpre-formed curve 215 within housing sleeve 220, e.g., towards housingsleeve proximal end 222 and away from housing sleeve distal end 221. Inone or more embodiments, a retraction of pre-formed curve 215 withinhousing sleeve 220 may be configured to retract a portion of pre-formedcurve 215 away from first housing sleeve portion 225, e.g., into aportion of housing sleeve 220 configured to generally straightenpre-formed curve 215. Illustratively, a retraction of a portion ofpre-formed curve 215 away from first housing sleeve portion 225, e.g.,into a portion of housing sleeve 220 configured to generally straightenpre-formed curve 215, may be configured to gradually straighten housingsleeve 220. In one or more embodiments, a gradual straightening ofhousing sleeve 220 may be configured to gradually straighten optic fiber230, e.g., from an optic fiber in a first partially straightenedposition 410 to an optic fiber in a second partially straightenedposition 420. In one or more embodiments, a line tangent to optic fiberdistal end 231 may intersect a line tangent to housing sleeve proximalend 222 at a second partially straightened angle, e.g., when optic fiber230 comprises an optic fiber in a second partially straightened position420. Illustratively, the second partially straightened angle maycomprise any angle less than the first partially straightened angle. Forexample, the second partially straightened angle may comprise a 90degree angle.

FIG. 4D illustrates an optic fiber in a third partially straightenedposition 430. In one or more embodiments, an actuation of actuationcontrol 120 within actuation control guide 140, e.g., towards actuationcontrol guide proximal end 142 and away from actuation control guidedistal end 141, may be configured to gradually straighten optic fiber230 from an optic fiber in a second partially straightened position 420to an optic fiber in a third partially straightened position 430.Illustratively, an actuation of actuation control 120 towards actuationcontrol guide proximal end 142 and away from actuation control guidedistal end 141 may be configured to retract actuation mechanism 110within actuation mechanism guide 160, e.g., towards handle proximal end102 and away from handle distal end 101. In one or more embodiments, aretraction of actuation mechanism 110 within actuation mechanism guide160 may be configured to retract shape memory wire 210 relative tohousing sleeve 220. Illustratively, a retraction of shape memory wire210 relative to housing sleeve 220 may be configured to retractpre-formed curve 215 within housing sleeve 220, e.g., towards housingsleeve proximal end 222 and away from housing sleeve distal end 221. Inone or more embodiments, a retraction of pre-formed curve 215 withinhousing sleeve 220 may be configured to retract a portion of pre-formedcurve 215 away from first housing sleeve portion 225, e.g., into aportion of housing sleeve 220 configured to generally straightenpre-formed curve 215. Illustratively, a retraction of a portion ofpre-formed curve 215 away from first housing sleeve portion 225, e.g.,into a portion of housing sleeve 220 configured to generally straightenpre-formed curve 215, may be configured to gradually straighten housingsleeve 220. In one or more embodiments, a gradual straightening ofhousing sleeve 220 may be configured to gradually straighten optic fiber230, e.g., from an optic fiber in a second partially straightenedposition 420 to an optic fiber in a third partially straightenedposition 430. In one or more embodiments, a line tangent to optic fiberdistal end 231 may intersect a line tangent to housing sleeve proximalend 222 at a third partially straightened angle, e.g., when optic fiber230 comprises an optic fiber in a third partially straightened position430. Illustratively, the third partially straightened angle may compriseany angle less than the second partially straightened angle. Forexample, the third partially straightened angle may comprise a 45 degreeangle.

FIG. 4E illustrates an optic fiber in a fully straightened position 440.In one or more embodiments, an actuation of actuation control 120 withinactuation control guide 140, e.g., towards actuation control guideproximal end 142 and away from actuation control guide distal end 141,may be configured to gradually straighten optic fiber 230 from an opticfiber in a third partially straightened position 430 to an optic fiberin a fully straightened position 440. Illustratively, an actuation ofactuation control 120 towards actuation control guide proximal end 142and away from actuation control guide distal end 141 may be configuredto retract actuation mechanism 110 within actuation mechanism guide 160,e.g., towards handle proximal end 102 and away from handle distal end101. In one or more embodiments, a retraction of actuation mechanism 110within actuation mechanism guide 160 may be configured to retract shapememory wire 210 relative to housing sleeve 220. Illustratively, aretraction of shape memory wire 210 relative to housing sleeve 220 maybe configured to retract pre-formed curve 215 within housing sleeve 220,e.g., towards housing sleeve proximal end 222 and away from housingsleeve distal end 221. In one or more embodiments, a retraction ofpre-formed curve 215 within housing sleeve 220 may be configured toretract a portion of pre-formed curve 215 away from first housing sleeveportion 225, e.g., into a portion of housing sleeve 220 configured togenerally straighten pre-formed curve 215. Illustratively, a retractionof a portion of pre-formed curve 215 away from first housing sleeveportion 225, e.g., into a portion of housing sleeve 220 configured togenerally straighten pre-formed curve 215, may be configured togradually straighten housing sleeve 220. In one or more embodiments, agradual straightening of housing sleeve 220 may be configured togradually straighten optic fiber 230, e.g., from an optic fiber in athird partially straightened position 430 to an optic fiber in a fullystraightened position 440. In one or more embodiments, a line tangent tooptic fiber distal end 231 may be parallel to a line tangent to housingsleeve proximal end 222, e.g., when optic fiber 230 comprises an opticfiber in a fully straightened position 440.

Illustratively, a surgeon may aim optic fiber distal end 231 at any of aplurality of targets within an eye, e.g., to perform a photocoagulationprocedure, to illuminate a surgical target site, etc. In one or moreembodiments, a surgeon may aim optic fiber distal end 231 at any targetwithin a particular transverse plane of the inner eye by, e.g., rotatinghandle 100 to orient housing sleeve 220 in an orientation configured tocause a curvature of housing sleeve 220 within the particular transverseplane of the inner eye and varying an amount of actuation of actuationcontrol 120. Illustratively, a surgeon may aim optic fiber distal end231 at any target within a particular sagittal plane of the inner eyeby, e.g., rotating handle 100 to orient housing sleeve 220 in anorientation configured to cause a curvature of housing sleeve 220 withinthe particular sagittal plane of the inner eye and varying an amount ofactuation of actuation control 120. In one or more embodiments, asurgeon may aim optic fiber distal end 231 at any target within aparticular frontal plane of the inner eye by, e.g., varying an amount ofactuation of actuation control 120 to orient a line tangent to opticfiber distal end 231 wherein the line tangent to optic fiber distal end231 is within the particular frontal plane of the inner eye and rotatinghandle 100. Illustratively, a surgeon may aim optic fiber distal end 231at any target located outside of the particular transverse plane, theparticular sagittal plane, and the particular frontal plane of the innereye, e.g., by varying a rotational orientation of handle 100 and varyingan amount of actuation of actuation control 120. In one or moreembodiments, a surgeon may aim optic fiber distal end 231 at any targetof a plurality of targets within an eye, e.g., without increasing alength of a portion of a steerable laser probe within the eye.Illustratively, a surgeon may aim optic fiber distal end 231 at anytarget of a plurality of targets within an eye, e.g., without decreasinga length of a portion of a steerable laser probe within the eye.

In one or more embodiments, one or more properties of a steerable laserprobe may be adjusted to attain one or more desired steerable laserprobe features. Illustratively, a relative location of pre-formed curve215 and first housing sleeve portion 225 may be modified, e.g., opticfiber 230 may comprise a straight optic fiber 300 when shape memory wire210 is fully extended relative to housing sleeve 220 and optic fiber 230may comprise a fully curved optic fiber 400 when shape memory wire 210is fully retracted relative to housing sleeve 220. For example, aportion of housing sleeve 220 located between housing sleeve distal end221 and first housing tube portion 225 may be configured to generallystraighten pre-formed curve 215.

In one or more embodiments, pre-formed curve 215 may be fully disposedin a portion of housing sleeve 220 configured to generally straightenpre-formed curve 215, e.g., when optic fiber 230 comprises a straightoptic fiber 300. Illustratively, an actuation of actuation control 120towards actuation control guide proximal end 142 and away from actuationcontrol guide distal end 141 may be configured to retract a portion ofpre-formed curve 215 over a portion of first housing sleeve portion 225,e.g., out from a portion of housing sleeve 220 configured to generallystraighten pre-formed curve 215. In one or more embodiments, aretraction of a portion of pre-formed curve 215 over a portion of firsthousing sleeve portion 225 may be configured to gradually curve housingsleeve 220. Illustratively, a gradual curving of housing sleeve 220 maybe configured to gradually curve optic fiber 230, e.g., from a straightoptic fiber 300 to an optic fiber in first curved position 310.

In one or more embodiments, pre-formed curve 215 may be fully disposedover first housing sleeve portion 225, e.g., when optic fiber 230comprises a fully curved optic fiber 400. Illustratively, an actuationof actuation control 120 towards actuation control guide distal end 141and away from actuation control guide proximal end 142 may be configuredto extend a portion of pre-formed curve 215 away from first housingsleeve portion 225, e.g., into a portion of housing sleeve 220configured to generally straighten pre-formed curve 215. In one or moreembodiments, an extension of a portion of pre-formed curve 215 into aportion of housing sleeve 220 configured to generally straightenpre-formed curve 215 may be configured to gradually straighten housingsleeve 220. Illustratively, a gradual straightening of housing sleeve220 may be configured to gradually straighten optic fiber 230, e.g.,from a fully curved optic fiber 400 to an optic fiber in a firstpartially straightened position 410.

The foregoing description has been directed to particular embodiments ofthis invention. It will be apparent; however, that other variations andmodifications may be made to the described embodiments, with theattainment of some or all of their advantages. Specifically, it shouldbe noted that the principles of the present invention may be implementedin any probe system. Furthermore, while this description has beenwritten in terms of a steerable laser probe, the teachings of thepresent invention are equally suitable to systems where thefunctionality of actuation may be employed. Therefore, it is the objectof the appended claims to cover all such variations and modifications ascome within the true spirit and scope of the invention.

What is claimed is:
 1. A laser probe comprising: an optic fiber havingan optic fiber distal end and an optic fiber proximal end wherein theoptic fiber is configured to transmit light; a housing sleeve having ahousing sleeve distal end, a housing sleeve proximal end, a firsthousing sleeve portion, and a second housing sleeve portion wherein thefirst housing sleeve portion has a first stiffness and the secondhousing sleeve portion has a second stiffness; a handle having a handledistal end and a handle proximal end; an actuation mechanism guide ofthe handle wherein the actuation mechanism guide is disposed between thehandle distal end and the handle proximal end; a housing sleeve housingof the handle wherein the housing sleeve housing is disposed between thehandle distal end and the actuation mechanism guide and wherein thehousing tube proximal end is disposed in the housing sleeve housing andwherein the housing tube proximal end is fixed in the housing sleevehousing; an actuation control guide having an actuation control guidedistal end and an actuation control guide proximal end; an actuationmechanism having an actuation mechanism distal end and an actuationmechanism proximal end wherein the actuation mechanism is disposed inthe actuation mechanism guide; an actuation control of the actuationmechanism wherein the actuation control is disposed in the actuationcontrol guide between the actuation control guide distal end and theactuation control guide proximal end; and an inner bore of the actuationmechanism wherein the optic fiber is disposed in the housing sleeve, thehousing sleeve housing, the actuation mechanism guide, and the innerbore.
 2. The laser probe of claim 1 wherein an actuation of theactuation control towards the actuation control guide distal end andaway from the actuation control guide proximal end is configured tocurve the optic fiber.
 3. The laser probe of claim 1 wherein anactuation of the actuation control towards the actuation control guidedistal end and away from the actuation control guide proximal end isconfigured to curve the housing sleeve.
 4. The laser probe of claim 1wherein an actuation of the actuation control towards the actuationcontrol guide proximal end and away from the actuation control guidedistal end is configured to straighten the optic fiber.
 5. The laserprobe of claim 1 wherein an actuation of the actuation control towardsthe actuation control guide proximal end and away from the actuationcontrol guide distal end is configured to straighten the housing sleeve.6. The laser probe of claim 1 further comprising: a pressure mechanismhousing of the handle; a pressure mechanism disposed in the pressuremechanism housing wherein the pressure mechanism is configured toprovide a force.
 7. The laser probe of claim 6 wherein an actuation ofthe actuation control towards the actuation control guide distal end andaway from the actuation control guide proximal end is configured tocurve the optic fiber.
 8. The laser probe of claim 6 wherein anactuation of the actuation control towards the actuation control guidedistal end and away from the actuation control guide proximal end isconfigured to curve the housing sleeve.
 9. The laser probe of claim 6wherein an actuation of the actuation control towards the actuationcontrol guide proximal end and away from the actuation control guidedistal end is configured to straighten the optic fiber.
 10. The laserprobe of claim 6 wherein an actuation of the actuation control towardsthe actuation control guide proximal end and away from the actuationcontrol guide distal end is configured to straighten the housing sleeve.11. The laser probe of claim 6 wherein the pressure mechanism is aspring.
 12. The laser probe of claim 11 wherein an actuation of theactuation control towards the actuation control guide distal end andaway from the actuation control guide proximal end is configured tocurve the optic fiber.
 13. The laser probe of claim 11 wherein anactuation of the actuation control towards the actuation control guidedistal end and away from the actuation control guide proximal end isconfigured to curve the housing sleeve.
 14. The laser probe of claim 11wherein an actuation of the actuation control towards the actuationcontrol guide proximal end and away from the actuation control guidedistal end is configured to straighten the optic fiber.
 15. The laserprobe of claim 11 wherein an actuation of the actuation control towardsthe actuation control guide proximal end and away from the actuationcontrol guide distal end is configured to straighten the housing sleeve.16. The laser probe of claim 1 further comprising: a shape memory wirehaving a shape memory wire distal end, a shape memory wire proximal end,and a pre-formed curve wherein the shape memory wire is at leastpartially disposed in the housing sleeve.
 17. The laser probe of claim16 wherein an actuation of the actuation control towards the actuationcontrol guide distal end and away from the actuation control guideproximal end is configured to curve the optic fiber.
 18. The laser probeof claim 16 wherein an actuation of the actuation control towards theactuation control guide distal end and away from the actuation controlguide proximal end is configured to curve the housing sleeve.
 19. Thelaser probe of claim 16 wherein an actuation of the actuation controltowards the actuation control guide proximal end and away from theactuation control guide distal end is configured to straighten the opticfiber.
 20. The laser probe of claim 16 wherein an actuation of theactuation control towards the actuation control guide proximal end andaway from the actuation control guide distal end is configured tostraighten the housing sleeve.